Cardiopulmonary Bypass Down-Regulates NOD Signaling and Inflammatory Response in Children with Congenital Heart Disease.

In the present study, we aimed to examine the impact of cardiopulmonary bypass (CPB) on expression and function of NOD1 and NOD2 in children with congenital heart disease (CHD), in an attempt to clarify whether NOD1 and NOD2 signaling is involved in the modulation of host innate immunity against pos...

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Bibliographic Details
Main Authors: Qinghua Yang, Jianyi Liao, Jie Huang, Yi Ping Li, Shungen Huang, Huiting Zhou, Yi Xie, Jian Pan, Yanhong Li, Jiang Huai Wang, Jian Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5021269?pdf=render