SIRT3 and RORα are two prospective targets against mitophagy during simulated ischemia/reperfusion injury in H9c2 cells

SIRT3 and RORα are two prospective targets against mitophagy during simulated ischemia/reperfusion injury in H9c2 cells

Autophagy during myocardial ischemia/reperfusion (MI/R) exacerbates cardiomyocyte injury. Melatonin (Mel) alleviates myocardial damage by regulating mitochondrial function and mitophagy, but the role of mitophagy in melatonin-induced cardioprotection remains unclear. This study aimed to explore the...

Full description

Bibliographic Details
Main Authors: Jinjing Wu, Yanli Yang, Duomao Lin, Zhaoqi Wang, Jun Ma
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Heliyon
Subjects:
Melatonin
Mitophagy
Ischemia reperfusion
Nuclear receptor
SIRT3
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402406599X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402406599X

Similar Items