The protective role of IL-1Ra on intestinal ischemia reperfusion injury by anti-oxidative stress via Nrf2/HO-1 pathway in rat

Background: Intestinal ischemia reperfusion injury is a frequent clinical damage, in which the oxidative stress and inflammation play an important role. Interleukin-1 receptor antagonist (IL-1Ra) is a natural anti-inflammatory factor, however, its effect on intestinal ischemia reperfusion injury rem...

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Bibliographic Details
Main Authors: Chen Jin, Wen-Liang Fu, Dong-Dong Zhang, Wei-Wei Xing, Wen-Rong Xia, Zhao Wei, Min-Ji Zou, Xiao-Ming Zhu, Dong-Gang Xu
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417018302932