The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells

The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells

Abstract Background Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely related with the cell cycle G2/M phase regulation. The present study aimed to...

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Bibliographic Details
Main Authors: Ruitao Zhang, Huirong Shi, Fang Ren, Minghui Zhang, Pengcheng Ji, Wenwen Wang, Chuanna Liu
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Ovarian Research
Subjects:
Cyclin dependent kinases 1
G2/M phase regulation
Ovarian epithelial cancer
Proliferation
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13048-017-0356-x

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http://link.springer.com/article/10.1186/s13048-017-0356-x

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