DNA Methylomes and Epigenetic Age Acceleration Associations with Poor Metabolic Control in T1D

DNA Methylomes and Epigenetic Age Acceleration Associations with Poor Metabolic Control in T1D

Type 1 diabetes (T1D) is an autoimmune disease that leads to insulin deficiency and hyperglycemia. Little is known about how this metabolic dysfunction, which substantially alters the internal environment, forces cells to adapt through epigenetic mechanisms. Consequently, the purpose of this work wa...

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Bibliographic Details
Main Authors: Raúl F Pérez, Juan Luis Fernandez-Morera, Judit Romano-Garcia, Edelmiro Menendez-Torre, Elias Delgado-Alvarez, Mario F Fraga, Agustin F Fernandez
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
type 1 diabetes
DNA methylation
PhenoAge
epigenetic aging
age acceleration
metabolic control
Online Access:https://www.mdpi.com/2227-9059/9/1/13

Internet

https://www.mdpi.com/2227-9059/9/1/13

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