A cathepsin C-like protease mediates the post-translation modification of Toxoplasma gondii secretory proteins for optimal invasion and egress

A cathepsin C-like protease mediates the post-translation modification of Toxoplasma gondii secretory proteins for optimal invasion and egress

ABSTRACT Microbial pathogens use proteases for their infections, such as digestion of proteins for nutrients and activation of their virulence factors. As an obligate intracellular parasite, Toxoplasma gondii must invade host cells to establish its intracellular propagation. To facilitate invasion,...

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Bibliographic Details
Main Authors: L. Brock Thornton, Melanie Key, Chiara Micchelli, Andrew J. Stasic, Samuel Kwain, Katherine Floyd, Silvia N.J. Moreno, Brian N. Dominy, Daniel C. Whitehead, Zhicheng Dou
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
Toxoplasma gondii
apicomplexan
protease
aminopeptidase
cathepsin C
protein trafficking
Online Access:https://journals.asm.org/doi/10.1128/mbio.00174-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00174-23

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