The role of the encephalomyocarditis virus type 1 proteins L and 2A in the inhibition of the synthesis of cellular proteins and the accumulation of viral proteins during infection

The role of the encephalomyocarditis virus type 1 proteins L and 2A in the inhibition of the synthesis of cellular proteins and the accumulation of viral proteins during infection

Introduction. Infection of cells with encephalomyocarditis virus type 1 (EMCV-1, Cardiovirus A: Picornaviridae) is accompanied by suppression of cellular protein synthesis. The main role in the inhibition of cellular translation is assigned to the L and 2A «security» proteins. The mechanism of the p...

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Bibliographic Details
Main Authors: Yury Yu. Ivin, Anna A. Butusova, Ekaterina E. Gladneva, Galina Ya. Kolomijtseva, Yusuf K. Khapchaev, Aydar A. Ishmukhametov
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2023-11-01
Series:Вопросы вирусологии
Subjects:
emcv-1
cardioviruses
picornaviruses
«security» proteins
leader protein
2a
translation inhibition
processing
Online Access:https://virusjour.crie.ru/jour/article/viewFile/446/282

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https://virusjour.crie.ru/jour/article/viewFile/446/282

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