CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

CCAAT/enhancer-binding protein δ (C/EBPδ) is a transcription factor involved in growth arrest and differentiation, which has consequently been suggested to harbor tumor suppressive activities. However, C/EBPδ over-expression correlates with poor prognosis in glioblastoma and promotes genomic instabi...

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Main Authors: Leonie Hartl, JanWillem Duitman, Hella L. Aberson, Kan Chen, Frederike Dijk, Joris J.T.H. Roelofs, Mark P.G. Dings, Gerrit K.J. Hooijer, Pratika Y. Hernanda, Qiunwei Pan, Olivier R. Busch, Marc G.H. Besselink, Ton Boerman, Maikel P. Peppelenbosch, Maarten F. Bijlsma, C. Arnold Spek
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2546