The time-course linkage between hemolysis, redox, and metabolic parameters during red blood cell storage with or without uric acid and ascorbic acid supplementation

The time-course linkage between hemolysis, redox, and metabolic parameters during red blood cell storage with or without uric acid and ascorbic acid supplementation

Oxidative phenomena are considered to lie at the root of the accelerated senescence observed in red blood cells (RBCs) stored under standard blood bank conditions. It was recently shown that the addition of uric (UA) and/or ascorbic acid (AA) to the preservative medium beneficially impacts the stora...

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Bibliographic Details
Main Authors: Alkmini T. Anastasiadi, Konstantinos Stamoulis, Effie G. Papageorgiou, Veronica Lelli, Sara Rinalducci, Issidora S. Papassideri, Anastasios G. Kriebardis, Marianna H. Antonelou, Vassilis L. Tzounakas
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Aging
Subjects:
red blood cell
glutathione
oxidative stress
uric acid
ascorbic acid
storage lesion
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2023.1161565/full

Internet

https://www.frontiersin.org/articles/10.3389/fragi.2023.1161565/full

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