Fermentative production and optimization of mevastatin in submerged fermentation using Aspergillus terreus

The main objective of the study is to enhance the mevastatin production using Plackett–Burman (PB) and central composite design (CCD) by Aspergillus terreus in submerged fermentation (SmF). Eight nutrients were chosen for a PB design with 12 experimental runs. A maximum mevastatin production of 170....

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Bibliographic Details
Main Authors: Mahin Basha Syed, M. Rajasimman
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X15000211