Fermentative production and optimization of mevastatin in submerged fermentation using Aspergillus terreus
The main objective of the study is to enhance the mevastatin production using Plackett–Burman (PB) and central composite design (CCD) by Aspergillus terreus in submerged fermentation (SmF). Eight nutrients were chosen for a PB design with 12 experimental runs. A maximum mevastatin production of 170....
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
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Series: | Biotechnology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2215017X15000211 |