Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations

Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations

We have previously shown that blood levels of B-cell Activating Factor (BAFF) rise relatively to disease progression status in the context of HIV-1 infection. Excess BAFF was concomitant with hyperglobulinemia and the deregulation of blood B-cell populations, notably with increased frequencies of a...

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Bibliographic Details
Main Authors: Kim Doyon-Laliberté, Matheus Aranguren, Josiane Chagnon-Choquet, Laurie-Anne Batraville, Olina Dagher, Jonathan Richard, Matteo Paniconi, Jean-Pierre Routy, Cécile Tremblay, Marie-Claude Quintal, Nathalie Brassard, Daniel E. Kaufmann, Andrés Finzi, Johanne Poudrier, Michel Roger
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Current Issues in Molecular Biology
Subjects:
BAFF
HIV-1
B-cells
marginal zone
antibodies
Online Access:https://www.mdpi.com/1467-3045/46/1/3

Internet

https://www.mdpi.com/1467-3045/46/1/3

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