Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets

Abstract Degeneration of the intervertebral disc is associated with a decrease in extra-cellular matrix (ECM) content due to an imbalance in anabolic and catabolic signaling. Our previous study profiled the core matrisome of fetal NP’s and identified various proteins with anabolic potential for rege...

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Bibliographic Details
Main Authors: Shanmuganathan Rajasekaran, Chitra Thangavel, Niek Djuric, Muthurajan Raveendran, Dilip Chand Raja Soundararajan, Sharon Miracle Nayagam, Monica Steffi Matchado, K. S. Sri Vijay Anand, Krishna Venkateshwaran
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97620-w