Peripheral signaling pathways contributing to non-histaminergic itch in humans

Peripheral signaling pathways contributing to non-histaminergic itch in humans

Abstract Background Chronic itch (chronic pruritus) is a major therapeutic challenge that remains poorly understood despite the extensive recent analysis of human pruriceptors. It is unclear how the peripheral nervous system differentiates the signaling of non-histaminergic itch and pain. Methods He...

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Bibliographic Details
Main Authors: Andrea Fiebig, Victoria Leibl, David Oostendorf, Saskia Lukaschek, Jens Frömbgen, Maral Masoudi, Andreas E. Kremer, Marion Strupf, Peter Reeh, Miriam Düll, Barbara Namer
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Microneurography
β-Alanine
BAM 8-22
Cowhage
Discharge patterns
Spatial contrast
Online Access:https://doi.org/10.1186/s12967-023-04698-z

Internet

https://doi.org/10.1186/s12967-023-04698-z

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