llperm: a permutation of regressor residuals test for microbiome data

Abstract Background Differential abundance testing is an important aspect of microbiome data analysis, where each taxa is fitted with a statistical test or a regression model. However, many models do not provide a good fit to real microbiome data. This has been shown to result in high false positive...

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Bibliographic Details
Main Authors: Markus Viljanen, Hendriek Boshuizen
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05088-w