llperm: a permutation of regressor residuals test for microbiome data
Abstract Background Differential abundance testing is an important aspect of microbiome data analysis, where each taxa is fitted with a statistical test or a regression model. However, many models do not provide a good fit to real microbiome data. This has been shown to result in high false positive...
Main Authors: | Markus Viljanen, Hendriek Boshuizen |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-05088-w |
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