Lyophilized Symbiotic Mitigates Mucositis Induced by 5-Fluorouracil

Mucositis is an adverse effect of cancer chemotherapies using 5-Fluorouracil (5-FU). It is characterized by mucosal inflammation, pain, diarrhea, and weight loss. Some studies reported promising healing effects of probiotic strains, when associated with prebiotics, as adjuvant treatment of mucositis...

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Main Authors: Bruna Savassi, Bárbara F. Cordeiro, Sara H. Silva, Emiliano R. Oliveira, Giovanna Belo, Alessandra Gomes Figueiroa, Maria Izabel Alves Queiroz, Ana Maria Caetano Faria, Juliana Alves, Tales Fernando da Silva, Gabriela Munis Campos, Erick A. Esmerino, Ramon S. Rocha, Monica Q. Freitas, Marcia C. Silva, Adriano G. Cruz, Kátia Duarte Vital, Simone O.A. Fernandes, Valbert N. Cardoso, Leonardo Borges Acurcio, Gwénaël Jan, Yves Le Loir, Alfonso Gala-Garcia, Fillipe Luiz R. do Carmo, Vasco Azevedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.755871/full