Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging

Candida albicans is a major fungal pathogen causing life-threatening diseases in immuno-compromised patients. The efficacy of current drugs to combat C. albicans infections is limited, as these infections have a 40–60% mortality rate. There is a real need for novel therapeutic approaches, but such a...

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Bibliographic Details
Main Authors: Stephane Dorsaz, Alix T. Coste, Dominique Sanglard
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01478/full