The evolution and diversity of the nonsense-mediated mRNA decay pathway [version 1; referees: 2 approved]

Nonsense-mediated mRNA decay is a eukaryotic pathway that degrades transcripts with premature termination codons (PTCs). In most eukaryotes, thousands of transcripts are degraded by NMD, including many important regulators of development and stress response pathways. Transcripts can be targeted to N...

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Bibliographic Details
Main Author: James P. B. Lloyd
Format: Article
Language:English
Published: F1000 Research Ltd 2018-08-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1299/v1