The evolution and diversity of the nonsense-mediated mRNA decay pathway [version 1; referees: 2 approved]
Nonsense-mediated mRNA decay is a eukaryotic pathway that degrades transcripts with premature termination codons (PTCs). In most eukaryotes, thousands of transcripts are degraded by NMD, including many important regulators of development and stress response pathways. Transcripts can be targeted to N...
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Format: | Article |
Language: | English |
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F1000 Research Ltd
2018-08-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-1299/v1 |