Stomatin inhibits pannexin-1-mediated whole-cell currents by interacting with its carboxyl terminal.

The pannexin-1 (Panx1) channel (often referred to as the Panx1 hemichannel) is a large-conductance channel in the plasma membrane of many mammalian cells. While opening of the channel is potentially detrimental to the cell, little is known about how it is regulated under physiological conditions. He...

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Bibliographic Details
Main Authors: Haiying Zhan, Craig S Moore, Bojun Chen, Xin Zhou, Xin-Ming Ma, Kumiko Ijichi, Michael V L Bennett, Xue-Jun Li, Stephen J Crocker, Zhao-Wen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387187?pdf=render