Exploring the Ocular Absorption Pathway of Fasudil Hydrochloride towards Developing a Nanoparticulate Formulation with Improved Performance

Exploring the Ocular Absorption Pathway of Fasudil Hydrochloride towards Developing a Nanoparticulate Formulation with Improved Performance

Rho-kinase (ROCK) inhibitors represent a new category of anti-glaucoma medications. Among them, Fasudil hydrochloride, a selective ROCK inhibitor, has demonstrated promising outcomes in glaucoma treatment. It works by inhibiting the ROCK pathway, which plays a crucial role in regulating the trabecul...

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Bibliographic Details
Main Authors: Barzan Osi, Ali A. Al-Kinani, Zinah K. Al-Qaysi, Mouhamad Khoder, Raid G. Alany
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceutics
Subjects:
ROCK
Fasudil hydrochloride
chitosan
nanoparticles
cornea absorption
ocular tolerability
Online Access:https://www.mdpi.com/1999-4923/16/1/112

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https://www.mdpi.com/1999-4923/16/1/112

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