Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell–cell interactions

Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell–cell interactions

Abstract Comprehensive screenings to clarify indirect cell–cell interactions, such as those in the tumor microenvironment, especially comprehensive assessments of supporting cells’ effects, are challenging. Therefore, in this study, indirect CRISPR screening for drug resistance with cell–cell intera...

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Bibliographic Details
Main Authors: Keisuke Sugita, Iichiroh Onishi, Ran Nakayama, Sachiko Ishibashi, Masumi Ikeda, Miori Inoue, Rina Narita, Shiori Oshima, Kaho Shimizu, Shinichiro Saito, Shingo Sato, Branden S. Moriarity, Kouhei Yamamoto, David A. Largaespada, Masanobu Kitagawa, Morito Kurata
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04941-9

Internet

https://doi.org/10.1038/s42003-023-04941-9

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