Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment

Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment

Abstract Background Inflammatory licensed mesenchymal stem cells (MSCs) have the ability to promote functional tissue repair. This study specifically sought to understand how the recipient tissue environment reciprocally affects MSC function. Inflammatory polarized macrophages, modeling an injured t...

Full description

Bibliographic Details
Main Authors: Jennifer M. Cassano, Lauren V. Schnabel, Margaret B. Goodale, Lisa A. Fortier
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Immunomodulation
Inflammatory licensing
Licensing
Polarization
Regenerative medicine
Online Access:http://link.springer.com/article/10.1186/s13287-018-0840-2

Internet

http://link.springer.com/article/10.1186/s13287-018-0840-2

Similar Items