Immunization with PfGBP130 generates antibodies that inhibit RBC invasion by P. falciparum parasites

Immunization with PfGBP130 generates antibodies that inhibit RBC invasion by P. falciparum parasites

BackgroundDespite decades of effort, Plasmodium falciparum malaria remains a leading killer of children. The absence of a highly effective vaccine and the emergence of parasites resistant to both diagnosis as well as treatment hamper effective public health interventions.Methods and resultsTo discov...

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Bibliographic Details
Main Authors: Yannick Johnson, Ahmad Rushdi Shakri, Sunthorn Pond-Tor, Anup Jnawali, Tanbir Najrana, Haiwei Wu, Jhasketan Badhai, Mohamad-Gabriel Alameh, Drew Weissman, Edward Kabyemela, Patrick Duffy, Michal Fried, Jonathan Kurtis, Dipak Kumar Raj
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
Subjects:
malaria
vaccine
blood stage malaria antigen
mRNA
growth inhibiting activity
Plasmodium falciparum
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1350560/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1350560/full

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