Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements

Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements

Abstract Background NRG1 fusion is a promising therapeutic target for various tumors but its prevalence is extremely low, and there are no standardized testing algorithms for genetic assessment. Mothods In this study, we analyzed 3008 tumors using Fluorescence in situ hybridization (FISH) and immuno...

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Bibliographic Details
Main Authors: Xiaomei Zhang, Lin Li, Fuping Gao, Binbin Liu, Jing Li, Shuang Ren, Shuangshuang Peng, Wei Qiu, Xiaohong Pu, Qing Ye
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Diagnostic Pathology
Subjects:
NRG1
Fluorescence in situ hybridization
Next generation sequencing
Online Access:https://doi.org/10.1186/s13000-023-01424-7

Internet

https://doi.org/10.1186/s13000-023-01424-7

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