STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats

STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats

Abstract Purpose Metabolic syndrome (MetS) became a tremendous public health burden in the last decades. Store-operated calcium entry (SOCE) is a unique mechanism that causes a calcium influx, which is triggered by calcium store depletion. MetS-induced alterations in cardiac calcium signaling, espec...

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Bibliographic Details
Main Authors: Aysegul Durak, Yusuf Olgar, Kardelen Genc, Erkan Tuncay, Fırat Akat, Sinan Degirmenci, Belma Turan
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cardiovascular Disorders
Subjects:
SOCE
Cardiac
Calcium
Metabolic syndrome
Online Access:https://doi.org/10.1186/s12872-022-02586-w

Internet

https://doi.org/10.1186/s12872-022-02586-w

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