Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis Virus

Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis Virus

St. Louis encephalitis virus (SLEV) is a neglected mosquito-borne Flavivirus that may cause severe neurological disease in humans and other animals. There are no specific treatments against SLEV infection or disease approved for human use, and drug repurposing may represent an opportunity to acceler...

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Bibliographic Details
Main Authors: Giuliana Eboli Sotorilli, Humberto Doriguetto Gravina, Ana Carolina de Carvalho, Jacqueline Farinha Shimizu, Marina Alves Fontoura, Talita Diniz Melo-Hanchuk, Artur Torres Cordeiro, Rafael Elias Marques
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Viruses
Subjects:
St. Louis encephalitis virus
cell culture-based screening
drug repurposing
Flavivirus
cationic amphiphilic compounds (CAD)
Online Access:https://www.mdpi.com/1999-4915/15/12/2416

Internet

https://www.mdpi.com/1999-4915/15/12/2416

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