Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer

Abstract Colorectal cancer (CRC) is the third most common cancer worldwide. Several studies have suggested that taraxasterol acetate (TA) can inhibit the growth of tumor cells. However, to date, it remains unclear how TA inhibits cell growth and how RNF31 functions as an oncogene. We examined the ex...

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Bibliographic Details
Main Authors: Chao-Tao Tang, Jing Yang, Zi-De Liu, Youxiang Chen, Chunyan Zeng
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00449-5