Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome accelerates bio-therapeutic threshold of apigenin in neoplastic rat liver: a mechanistic approach

Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome accelerates bio-therapeutic threshold of apigenin in neoplastic rat liver: a mechanistic approach

Abstract Hepatocellular carcinoma (HCC) is a leading cause of death globally. Even though the progressive invention of some very potent therapeutics has been seen, the success is limited due to the chemotherapeutic resistance and recurrence in HCC. Advanced targeted treatment options like immunother...

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Bibliographic Details
Main Authors: Moumita Dhara, Ashique Al Hoque, Ramkrishna Sen, Debasmita Dutta, Biswajit Mukherjee, Brahamacharry Paul, Soumik Laha
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Nanobiotechnology
Subjects:
Aptamer
Apigenin
Stealth nanoliposomes
Intratumor drug accumulation
Apoptosis
Pharmacokinetics
Online Access:https://doi.org/10.1186/s12951-022-01764-4

Internet

https://doi.org/10.1186/s12951-022-01764-4

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