Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions

Folate (vitamin B9) is involved in one-carbon transfer reactions and plays a significant role in nucleic acid synthesis and control of cellular proliferation, among other key cellular processes. It is now recognized that the role of folates in different stages of carcinogenesis is complex, and more...

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Bibliographic Details
Main Authors: Blake R. Rushing, Halle M. Fogle, Jaspreet Sharma, Mikyoung You, Jonathan P. McCormac, Sabrina Molina, Susan Sumner, Natalia I. Krupenko, Sergey A. Krupenko
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/23/8394