Enhanced Antibacterial Activity of Dermaseptin through Its Immobilization on Alginate Nanoparticles—Effects of Menthol and Lactic Acid on Its Potentialization

Dermaseptin B2 (DRS-B2) is an antimicrobial peptide secreted by <i>Phyllomedusa bicolor</i>, which is an Amazonian tree frog. Here, we show that the adsorption of DRS-B2 on alginate nanoparticles (Alg NPs) results in a formulation (Alg NPs + DRS-B2) with a remarkable antibacterial activi...

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Bibliographic Details
Main Authors: Noura Hazime, Yanath Belguesmia, Alexandre Barras, Mohamed Amiche, Rabah Boukherroub, Djamel Drider
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/6/787