Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis

Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis

Abstract Most cancer cells perform glycolysis despite having sufficient oxygen. The specific metabolic pathways of cancer cells have become the focus of cancer treatment. Recently, accumulating evidence indicates oxidative phosphorylation (OXPHOS) and glycolysis can be regulated with each other. Thu...

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Bibliographic Details
Main Authors: Ye Kuang, Xiaoyun Han, Mu Xu, Qing Yang
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Cancer Medicine
Subjects:
Akt/HIF pathway
apoptosis
glycolysis
oxaloacetate
oxidative phosphorylation
Online Access:https://doi.org/10.1002/cam4.1410

Internet

https://doi.org/10.1002/cam4.1410

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