Lower-limb amputations in patients treated with SGLT2 inhibitors versus DPP-4 inhibitors: A meta-analysis of observational studies

Summary: Background: An increased risk of lower limb amputations (LLA) has been suspected with the use of sodium-glucose cotransporter type 2 inhibitors (SGLT2is) in the CANVAS programme with canagliflozin and in pharmacovigilance reports with all SGLT2is. Even if reassuring observations were repor...

Full description

Bibliographic Details
Main Author: Andre J. Scheen
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Diabetes Epidemiology and Management
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666970622000051