Dual role of topoisomerase II in centromere resolution and aurora B activity.

Chromosome segregation requires sister chromatid resolution. Condensins are essential for this process since they organize an axial structure where topoisomerase II can work. How sister chromatid separation is coordinated with chromosome condensation and decatenation activity remains unknown. We com...

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Bibliographic Details
Main Authors: Paula A Coelho, Joana Queiroz-Machado, Alexandre M Carmo, Sara Moutinho-Pereira, Helder Maiato, Claudio E Sunkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18752348/?tool=EBI