GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli

GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli

Adipose tissue (AT) dysfunctions are associated with the onset of insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Targeting glucose-dependent insulinotropic peptide receptor (GIPR) is a valid option to increase the efficacy of glucagon-like peptide 1 (GLP-1) receptor agonists in T2DM tr...

Full description

Bibliographic Details
Main Authors: Simona Cataldi, Marianna Aprile, Caterina Perfetto, Brice Angot, Mireille Cormont, Alfredo Ciccodicola, Jean-Francois Tanti, Valerio Costa
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
GIP receptor
Inflammation
Hypertrophic adipocytes
Thiazolidinediones
PPARγ
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000353

Internet

http://www.sciencedirect.com/science/article/pii/S0171933523000353

Similar Items