q-Diffusion leverages the full dimensionality of gene coexpression in single-cell transcriptomics

Abstract Unlocking the full dimensionality of single-cell RNA sequencing data (scRNAseq) is the next frontier to a richer, fuller understanding of cell biology. We introduce q-diffusion, a framework for capturing the coexpression structure of an entire library of genes, improving on state-of-the-art...

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Bibliographic Details
Main Authors: Myrl G. Marmarelis, Russell Littman, Francesca Battaglin, Donna Niedzwiecki, Alan Venook, Jose-Luis Ambite, Aram Galstyan, Heinz-Josef Lenz, Greg Ver Steeg
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06104-w