IGFBP7 and the Tumor Immune Landscape: A Novel Target for Immunotherapy in Bladder Cancer

IGFBP7 and the Tumor Immune Landscape: A Novel Target for Immunotherapy in Bladder Cancer

Insulin-like growth factor binding protein-7 (IGFBP7) was recently reported to be a ligand of CD93, a potential target to normalize vasculature and attenuate immunotherapy. However, its role in the tumor microenvironment (TME) and immunotherapy response of bladder cancer (BLCA) remains unclear. We c...

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Bibliographic Details
Main Authors: Xianyanling Yi, Xiaonan Zheng, Hang Xu, Jin Li, Tianyi Zhang, Peng Ge, Dazhou Liao, Hong Li, Xiaoyan Lyu, Jianzhong Ai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
IFGBP7
bladder cancer
immunotherapy
tumor microenvironment
molecular subtype
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.898493/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.898493/full

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