New Imide 5-HT1A Receptor Ligands – Modification of Terminal Fragment Geometry

New Imide 5-HT1A Receptor Ligands – Modification of Terminal Fragment Geometry

Two sets of new o-methoxyphenylpiperazine (MPP; series a) and 1,2,3,4-tetrahydroisoquinoline (THIQ; series b) derivatives, containing various imide moietiesderived from NAN190, were synthesized and evaluated in vitro for their ability to bind tothe serotonin 5-HT1A and 5-HT2A receptors. All new deri...

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Bibliographic Details
Main Authors: Ryszard Bugno, Aneta Kozioł, Beata Duszyńska, Maria J. Mokrosz, Andrzej J. Bojarski
Format: Article
Language:English
Published: MDPI AG 2004-02-01
Series:Molecules
Subjects:
5-HT1A ligands
arylpiperazine derivatives
1
2
3
4-tetrahydroisoquinoline derivatives.
Online Access:http://www.mdpi.com/1420-3049/9/3/170/

Internet

http://www.mdpi.com/1420-3049/9/3/170/

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