Longitudinal Variations of M. tuberculosis-Induced IFN-γ Responses in HIV-Negative Pregnant Women Exposed to Tuberculosis

Longitudinal Variations of M. tuberculosis-Induced IFN-γ Responses in HIV-Negative Pregnant Women Exposed to Tuberculosis

IntroductionPregnancy triggers an alteration of the immune functions and increases the risk of developing the active tuberculosis (TB) symptoms in exposed women. The effect of pregnancy on the Mycobacterium tuberculosis-specific immune responses used for most of the TB immunodiagnostic assays is not...

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Bibliographic Details
Main Authors: Paulo Ranaivomanana, Rila Ratovoson, Crisca Razafimahatratra, Arimanitra Razafimahefa, Jonathan Hoffmann, Perlinot Herindrainy, Julio Rakotonirina, Niaina Rakotosamimanana
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
interferon-gamma release assays (IGRA)
pregnancy
human whole blood
QuantiFERON-TB Gold Plus®
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.805157/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.805157/full

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