Infrapatellar fat pad adipose-derived stem cells co-cultured with articular chondrocytes from osteoarthritis patients exhibit increased chondrogenic gene expression

Abstract Aim The variable results in clinical trials of adipose tissue-derived stem cells (ASCs) for chondral defects may be due to the different ex vivo culture conditions of the ASCs which are implanted to treat the lesions. We sought to determine the optimal in vitro chondrocyte co-culture condit...

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Bibliographic Details
Main Authors: Christopher C. H. Mak, Kendrick To, Karim Fekir, Roger A. Brooks, Wasim S. Khan
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-021-00815-x