Microevolution of Cryptococcus neoformans in high CO2 converges on mutations isolated from patients with relapsed cryptococcosis

Summary: Cryptococcus neoformans is an environmental fungus that causes an estimated 180,000 deaths annually and transitions from the external environment to the host environment to cause disease. CO2 concentrations in the atmosphere (0.04%) are dramatically lower than in mammalian tissues (5%). Env...

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Bibliographic Details
Main Authors: Benjamin J. Chadwick, Laura C. Ristow, Emma E. Blackburn, Xiaofeng Xie, Damian J. Krysan, Xiaorong Lin
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725001202