Activation of cGAS-STING Pathway Is Associated with MSI-H Stage IV Colorectal Cancer

Activation of cGAS-STING Pathway Is Associated with MSI-H Stage IV Colorectal Cancer

Colorectal cancer is the second most common cause of cancer-related mortality in adults. Understanding colorectal tumorigenesis at both the cellular and molecular levels is crucial for developing effective treatment options. Forty-one biopsy samples from patients with metastatic CRC (mCRC) were coll...

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Bibliographic Details
Main Authors: Nenad Kunac, Marina Degoricija, Jelena Viculin, Jasminka Omerović, Janoš Terzić, Katarina Vilović, Jelena Korac-Prlic
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
colorectal cancer
cGAS-STING pathway
microsatellite instability
immune checkpoint inhibitors
biomarkers
Online Access:https://www.mdpi.com/2072-6694/15/1/221

Internet

https://www.mdpi.com/2072-6694/15/1/221

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