Vitamin D3 deficiency induced intestinal inflammatory response of turbot through nuclear factor-κB/inflammasome pathway, accompanied by the mutually exclusive apoptosis and autophagy

Vitamin D3 deficiency induced intestinal inflammatory response of turbot through nuclear factor-κB/inflammasome pathway, accompanied by the mutually exclusive apoptosis and autophagy

Vitamin D3 (VD3) participated widely in the nuclear factor-κB (NF-κB)-mediated inflammation, apoptosis, and autophagy through the vitamin D receptor (VDR). However, the molecular mechanisms remain not understood in teleost. The present study investigated the functions of VD3/VDR on intestinal inflam...

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Bibliographic Details
Main Authors: Zhichu Chen, Dong Huang, Prakaiwan Yongyut, Guangbin Li, María Ángeles Esteban, Orapint Jintasataporn, Junming Deng, Wenbing Zhang, Qinghui Ai, Kangsen Mai, Yanjiao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
vitamin D3
vitamin D3 receptor
NF-κB
inflammasome
inflammation
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.986593/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.986593/full

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