Meta-Analysis of the Effects of the Catechol-O-Methyltransferase Val158/108Met Polymorphism on Parkinson’s Disease Susceptibility and Cognitive Dysfunction

Background: There is a continued debate and inconsistent findings in previous literature about the relationship of catechol-O-methyltransferase (COMT) and Parkinson’s disease (PD) susceptibility as well as cognitive dysfunction. To substantiate this existing gap, we comprehensively examine COMT geno...

Full description

Bibliographic Details
Main Authors: Chuanxi Tang, Wei Wang, Mingyu Shi, Na Zhang, Xiaoyu Zhou, Xue Li, Chengcheng Ma, Gang Chen, Jie Xiang, Dianshuai Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00644/full