Kaposi's sarcoma-associated herpes virus-derived microRNA K12–1 over-activates the PI3K/Akt pathway to facilitate cancer progression in HIV-related gastrointestinal Kaposi's sarcoma

Background: Kaposi's sarcoma-associated herpes virus (KSHV) initiate and accelerate the development of Kaposi's sarcoma (KS), and KSHV possesses many cancer-associated genes, including KSHV-derived microRNA miR-K12–1, which has been identified to be closely associated with KS progression....

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Bibliographic Details
Main Authors: Xiaoling Huang, Wei Rao, Chun Wang, Jiajie Lu, Ziqiong Li, Wenjie Kong, Yan Feng, Tian Xu, Rziya Apaer, Feng Gao
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:SLAS Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555222136609