Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies

Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies

Infantile onset hereditary spastic paralysis (IAHSP) is a rare neurological disease diagnosed in less than 50 children worldwide. It is transmitted with a recessive pattern and originates from mutations of the <i>ALS2</i> gene, encoding for the protein alsin and involved in differentiati...

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Bibliographic Details
Main Authors: Matteo Rossi Sebastiano, Giuseppe Ermondi, Kai Sato, Asako Otomo, Shinji Hadano, Giulia Caron
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
infantile onset ascending hereditary spastic paralysis
ALS2
virtual screening
vitamin K
drug repurposing
personalized medicine
Online Access:https://www.mdpi.com/1420-3049/27/20/7063

Internet

https://www.mdpi.com/1420-3049/27/20/7063

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