Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies
Infantile onset hereditary spastic paralysis (IAHSP) is a rare neurological disease diagnosed in less than 50 children worldwide. It is transmitted with a recessive pattern and originates from mutations of the <i>ALS2</i> gene, encoding for the protein alsin and involved in differentiati...
Main Authors: | Matteo Rossi Sebastiano, Giuseppe Ermondi, Kai Sato, Asako Otomo, Shinji Hadano, Giulia Caron |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/20/7063 |
Similar Items
-
Clinical features and molecular genetic investigation of infantile-onset ascending hereditary spastic paralysis (IAHSP) in two Chinese siblings caused by a novel splice site ALS2 variation
by: Qiang Zhang, et al.
Published: (2024-01-01) -
Symmetric Ascending Paralysis Secondary to West Nile Virus
by: Alex Ashkin, et al.
Published: (2023-07-01) -
Genetic and clinical features of pediatric-onset hereditary spastic paraplegia: a single-center study in Japan
by: Azusa Ikeda, et al.
Published: (2023-05-01) -
Intrathecal Baclofen in Hereditary Spastic Paraparesis
by: Elke Pucks-Faes, et al.
Published: (2019-08-01) -
DIAGNOSTICS AND TREATMENT OF SPASTIC HAND IN CHILDREN WITH INFANTILE CEREBRAL PARALYSIS: THE REVIEW. PART 1. THE ASSESSMENT OF UPPER EXTREMITY STATE
by: D. V. Umnov, et al.
Published: (2016-11-01)