Computational screening of biomarkers and potential drugs for arthrofibrosis based on combination of sequencing and large nature language model

Background: Arthrofibrosis (AF) is a fibrotic joint disease resulting from excessive collagen production and fibrous scar formation after total knee arthroplasty (TKA). This devastating complication may cause consistent pain and dramatically reduction of functionality. Unfortunately, the conservativ...

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Bibliographic Details
Main Authors: Xi Chen, Cheng Li, Ziyuan Wang, Yixin Zhou, Ming Chu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23000918