Identification of pyroglutamyl peptides with anti-colitic activity in Japanese rice wine, sake, by oral administration in a mouse model

Identification of pyroglutamyl peptides with anti-colitic activity in Japanese rice wine, sake, by oral administration in a mouse model

Two pyroglutamyl peptides with anti-colitic activity were identified in Japanese rice wine, sake, by oral administration of a small dose (0.1–1.0 mg/kg body weight) and in vivo activity-guided fractionation. Compounds in sake were fractionated by preparative isoelectric focusing followed by preparat...

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Bibliographic Details
Main Authors: Tamami Kiyono, Sayori Wada, Ryoko Ohta, Eri Wada, Tomohisa Takagi, Yuji Naito, Toshikazu Yoshikawa, Kenji Sato
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Functional Foods
Subjects:
Pyroglutamyl peptide
Colitis
Sake
Japanese rice wine
Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616303279

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http://www.sciencedirect.com/science/article/pii/S1756464616303279

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