ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus

ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus

Amidst rising cases of antimicrobial resistance, antimicrobial peptides (AMPs) are regarded as a promising alternative to traditional antibiotics. Even so, poor pharmacokinetic profiles of certain AMPs impede their utility necessitating, a careful assessment of potential AMPs’ absorption, distributi...

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Bibliographic Details
Main Authors: Hedmon Okella, Emmanuel Okello, Andrew Glory Mtewa, Hilda Ikiriza, Bruhan Kaggwa, Jacqueline Aber, Christian Ndekezi, Joseph Nkamwesiga, Clement Olusoji Ajayi, Ivan Mulongo Mugeni, Geofrey Ssentamu, Sylvester Ochwo, Steven Odongo, Casim Umba Tolo, Charles Drago Kato, Patrick Ogwang Engeu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
ADMET profiling
African catfish
antimicrobial peptides
novel leads
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1039286/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.1039286/full

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