Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils
Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice. Ectosomes, microvesicles released from neutrophil...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-10-01
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Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/1753425920936754 |